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* e coli, item room, treasure room, item room pool, tampon, bloody, red, white, red sperm, ecoli, Isaac's tears turn into large scythes that pierce through enemies (Similar to how Death's scythes look), UNLOCK: Unlock this item by beating Challenge #17 (Waka Waka), * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, axe, silver, Magic Fingers ignores the +40 flat damage with Ipecac, removing the synergy between these two, * shop room pool, shop item pool, item room, treasure room, item room pool, tissue, soul or black hearts, Your devil deal chance isn't ruined by this item taking away red hearts. Blue Baby, The Lost), * devil pool, devil room pool, devil deal, red, black, star, moon, When used, gives a random familiar for the entire floor. knife, red, silver, Gives a 33% chance of converting red heart drops into soul hearts. ?, Satan and The Lamb as Tainted Lilith, All shops only sell familiars while holding this trinket, If you enter a shop while holding this trinket, the effect won't undo by dropping it until you move to a new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lilith, Every time an enemy dies you have a chance to gain a random Locust, Different color Locusts correspond to the horsemen. Essentially you are rerolling all your items, but each new item you get to choose between 3 random options, The bedroom also contains a random trinket, 2 chests, 2 sacks and Isaac's bed, which can be used to full heal your red heart health, The only way to exit Isaac's bedroom is teleporting out or via the trapdoor, which takes you to the next floor. yellow book how to, * boss room pool, boss room item, bone, red, brown, Gives Isaac a random tarot card when picked up, * boss room pool, boss room item, eight, grey, gray, Drops 4 random pills on the floor around Isaac, Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch, moms coin purse, mom coin purse. The platinum god website doesn't have it,same goes for the wiki,so if anyone got that yet it would be nice if you told me what the item is. Guarantees a Planetarium if an item room has been skipped, otherwise +15% chance for Planetariums to spawn while held. grey, gray, green, mouth, bobs rotten head, bob rotten head, Teleports Isaac to a random location on the map, Can't be used to teleport to the I AM ERROR room, REPENTANCE - Teleport! REPENTANCE - The Inner Eye now causes less of a decrease in rate of fire than previously, and now has a tighter spread. One of the best parts of the Binding of Isaac is the huge number of item interactions and synergies you can get by combining certain items, however they don't always work as expected. Taking damage noise at this size is rather cursed.. Bombs, keys, cards, runes and batteries have a 20% chance, Can lead to game-breaking combinations with the D20 due to the amount of consumables and batteries spawned by the item sacks, REPENTANCE - Added to the Secret Room pool. Isaac's head will remain stationary and fire tears. For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purle appearance. Type: Active. communion, the lost item pool, circle, cross, white, yellow, +0.04 Damage Up for every coin you currently have, At 99 coins this item gives +3.96 Damage Up, +0.04 per coin is the amount added before the damage formula is calculated, as this is the only way to show a consistent amount of damage given. While at full red health you also shoot a projectile across the room with each swing, dealing your current Damage + 2 (similar to the Master Sword in Zelda), UNLOCK: Unlock this item by defeating challenge #39 (Isaac's Awakening), While held, a red outline of a door will appear on certain walls. How to see what items do in Binding of isaac. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, The item's color scheme matches the D8 die included in The Binding of Isaac: Four Souls card game, which is used as a spindown dice to keep track of an enemy's health. In exchange it gives you +0.05 Speed Up and Damage Up for every half a heart this item removes, The amount of Damage Up is (0.15 * FullHeartsRemoved ^ 2), If Isaac is already at half a red heart when stabbed, no damage or speed increases are given, The damage from being stabbed can be avoided with invincibility, however no damage or speed stat increases are gained if you do, Your individual tears each gain a random effect from either: Poison, Fear, Slow, Freeze, Charm, Burning, Homing, Bleeding, x2 Damage or Reduced damage, Allows you to walk on harmful floor effects without taking damage (e.g. Holy Mantle is the ultimate defensive-based item. UNLOCK: Unlock this item by defeating Delirium in The Void floor with Isaac, A one time use active item that when used, will spawn 2 random item pedestals from the item pool associated with the current room (e.g. They also no longer block player attacks or get extinguished by them, UNLOCK: Unlock this item by donating 400 pennies to the Shop, Isaac can now pick up hearts while at full health, which will be stored in the Jar and can be spawned again using the spacebar, Soul hearts and black hearts cannot be stored, If used in a Black heart or Eternal heart super secret room, it will spawn the relevant heart, * shop room pool, shop item pool, the lost item pool, glass. This means if you roll into The Lost, changing back to another character will leave you with only 1/2 of a soul heart, Cannot turn you into a character that isn't unlocked yet, Also includes Lazarus II (Lazarus' revived form) and Dark Judas (effect of Judas' Shadow), It's also possible that this item will pick the same character, making it seem like nothing happened, *, grey, gray, black, remote, zapper, changer, building, A one time use item that when used will explode all objects (i.e. UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith, Item Pool: Item Room, Red Chest, Curse Room, During the transition between floors, this item shows you a preview of the item that will spawn in the item room, and the boss that will appear, This effect will work even if you have Curse of the Blind, but the item will still appear as a ? 531. with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. Replacing all 12 containers with broken hearts will kill you instantly. Unlocked from the 'U broke it!' This works with all normal pickups, including cards, runes, chests and trinkets. Cain - +1 Luck. Mr. Peppino in The Binding of Isaac : r/thebindingofisaac Amnesia becomes I Can See Forever etc, Adds 0-2 coins to the payout when you use a Blood Donation machine or IV Bag, * shop room pool, shop item pool, item room, treasure room, item room pool, pink, yellow, paper, Reveals the entrance to secret rooms and automatically opens the hole, removing the need for bombs to enter, * item room, treasure room, item room pool, xray vision, xray glasses, pink, white, black, Gives Isaac invincibility and +0.28 Speed for 6 seconds, While active you cannot fire tears, but running into enemies will deal 40 contact damage per second, Allows free hits on the Blood Donation machines and devil beggars, * item room, treasure room, item room pool, white, horn, Upon use, gives Isaac an extra Soul heart, Using this item gives you a higher chance of finding a horsemen boss at the end of the floor, +17.5% chance of a Devil Deal opening after the boss fight, UNLOCK: Unlock this item by beating one of the horsemen bosses for the first time, Item Pool: Item Room, Library, Angel Room, * library pool, library room, book room pool, item room, treasure room, item room pool, or Satan), The Wafer becomes most effective in the Womb and beyond where enemies all deal a whole heart of damage, The Wafer causes the Sharp Plug item to only cost 1/2 a heart per use, Has no effect with the Keeper - there's no such thing as half a coin health point, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Mod support for nearly all mods! The locust fly will do different things for each harbinger - e.g. debug 2 - Displays the number of each cell. When the effect wears off, Isaac quickly runs between each marked enemy, dealing high damage to each one rapidly (roughly x2.5 your tear damage), The damage caused by this effect scales up with every target it hits in a row, UNLOCK: Unlock this item by defeating Delirium as Tainted Judas, *, budas, jubas, sword, blood, omae wa mou shindeiru, When used, Abyss consumes all pedestal items in the current room and converts them into Red attack flies, Red attack flies will charge across the room in the same direction Isaac is shooting, dealing contact damage to enemies equal to Isaac's tear damage, The flies don't block enemy shots, but this also means they never die and stay with Isaac forever, UNLOCK: Unlock this item by defeating Delirium as Tainted Apollyon, Staples one of Isaac's eyes shut, meaning he only shoots tears from one eye. Deals significant contact damage to enemies while active (1600 dps). The Red Key item is required to access it, but it shows the direction to get there, UNLOCK: Unlock this item by defeating The Beast as Eve, Upon entering each new floor, if you have one red heart or less, another one is added, This effect works while moving up floors in the backwards path, This item has no effect for characters with non-red health i.e. How do you spawn/create an item pedestal? : r/themoddingofisaac - reddit princezzxdiana, pink, purple, hat, Once per room when you are damaged down to your final half a heart, you gain 1 soul heart, Re-entering a room allows this effect to be triggered again. UNLOCK: Unlock this item by defeating Mother in the Corpse II as Eve, When used, this item does a shout-type attack, with its effect increasing in damage and size the more charges you have, Larynx can be used with any number of charges. ?? 2 keys = 50% chance. I won't go into depth, but maybe in the on-coming future I will. 410. Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms, Can move any of the following: Batteries, Items, Trinkets, Hearts, Keys, Bombs, Coins, Chests and more, Using Moving Box with Car Battery will trigger 2 interactions at the same time: First it will drop all items currently inside the box and secondly will then pick up the current room's contents, When used in a room with 2 items you can choose from (e.g. Each secret room contains a beam of light, that gives half a soul heart, and a Tears Up for the rest of the floor. The effect triggers again 30 seconds after use and again 60 seconds after use, Something's wrong - Spawns a pool of black creep beneath Isaac, Vurp! The priority list of what will drop from champion enemies in order is as follows: Soul Hearts - When you have no red heart containers and less than 2 soul hearts, Red Hearts (Full hearts) - While at 0.5 red hearts, Red Hearts (Full hearts) - When you have at least half a red heart container empty, Trinkets - If you have no trinkets and there are no trinkets on the ground in the room, Soul Hearts - When you have less than 6 total heart containers of any kind, If none of the above conditions are true, champions will resume dropping their regular pickups, UNLOCK: Unlock this item by defeating Greedier mode with Maggy, Allows you to fire tears diagonally by holding down two of the fire buttons at once, If you are using a gamepad, this item allows you to fire in any direction, The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode, If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go, Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. This includes damage you deal, and environmental damage they take e.g. The item order is based on the original The Binding of Isaac up to item 129 ( A Lump of Coal ), and its expansion, Wrath of the Lamb, up to item 195 ( Box ). No longer drops black hearts like it used to. debug 3 - Full invulnerability. Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation. With poison effects, the damage over time poison will last for much longer. One choice. : r/thebindingofisaac Every so often it will come up and attempt to grab onto a random enemy in the room, holding them in place and dealing damage, The Worm Friend deals 4 damage for 8 ticks total, If the enemy moves quickly enough it can miss its attack, UNLOCK: Unlock this item by defeating The Beast as Apollyon, Enemies that die will leave behind 1-2 floating bone shards where they die, until you leave the room, Other enemies that touch the bone shards will take 3.5 damage, with a chance to either bounce off them or cause it to break and disappear, UNLOCK: Unlock this item by defeating Mother as The Forgotten, Each time an enemy dies, a friendly red soul appears. Possible doors include any needing a key to open (Item Room, Shop, Alt Path doors), secret rooms and crawl spaces, Cracked Orb can also reveal the location of the red room that contains a pedestal item. Gives a one-time use of the D6 and D20 effects at the same time, When used will cause two of Mom's Hand to come down and grab a random enemy, Grants the Holy Mantle effect for, which will negate your next hit of damage, Tainted Lost starts with this card, and while playing as this character all cards and runes have a 10% chance to turn into a Holy Card, UNLOCK: Unlock this item by defeating Delirium in The Void floor with The Lost. Thanks in advance. - When used will consume your current trinket, destroying it and giving you its effect permanently. UNLOCK: Unlock this item by defeating the Isaac boss with Blue Baby. Unlocked from the 'Once more with the feeling!' Soul Hearts that are used to charge Spirit Shackles will not be added to your health as normal, UNLOCK: Unlock this item by defeating The Beast as The Forgotten, Taking damage reveals a random room on the minimap, and automatically opens certain doors in the current room. It can take you to rooms that require bombs/keys, e.g. Be warned though, Mom's leg can also stomp and hurt Isaac too! purple, An orbiting fly which deals 2 contact damage per tick to enemies, * item room, treasure room, item room pool, blue, Has a chance to drop from the Super Gluttony miniboss fight, Item Pool: Item Room, Super Gluttony Miniboss, * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub, Allows Isaac to fly while the Pony is held, Sets your speed stat to 1.5 if it isn't already that high, When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits, Drops from the Headless Horseman boss fight, REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). While held there is a small chance when using a tarot card or pill that a copy of it will be dropped on the floor next to you, +0.2 Damage Up for each 'evil' item you have, Items classed as evil in this case are Black Candle, Ceremonial Robes, Abaddon, Goat Head, Match Book, Missing Page 2, Safety Pin, UNLOCK: Unlock this item by beating Greed Mode with Eve, Invincibility lasts longer after getting hit (Increased i-frames), This makes it possible to use the Blood Donation machine twice from one hit of damage, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Samson, *, bandana, sling, white, knot, blindfold, +15% chance to get a double item room to spawn on the next floor, If the effect activates, two items spawn in your item room, however only one can be taken (Same effect as the More Options item), The chance doubles to +30% with the effect from Mom's Box, Automatically opens all shop room doors for free, UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this trinket after beating Satan with Keeper, Forces the Greed and Super Greed mini bosses to no longer appear in shops or secret rooms, Holding Rib of Greed increase your chance to receive coin drops, UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper, Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar, UNLOCK: Unlock this item by beating The Lamb boss with Keeper, Destroying poops now gives you a blue fly, While held, you heal for half a red heart every time you use a key to open a door or golden chest, Changes all half red hearts into full hearts, Hearts dropped from Tainted Magdalene's mechanic will be always full red hearts, *, red, brown, grey, gray, necklace, moms locket, mom locket, While this trinket is held you have a significantly lower chance to find spacebar/active items, It will cause passive items to spawn except when the game cannot generate any more passive items and will then instead choose spacebar/active items, Some hard coded spacebar items from bosses and mini-bosses (i.e.