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The Stanley Center engages in large-scale, globally conducted studies of . Cambridge, MA 02142. 908: Frequently searched careers. LinkedIn profile Oana Ursu Status: Postdoc, Aviv Regev lab, Broad Institute Lab Affiliation: PhD, Genetics Dept., Co-advised by Mike Snyder Sept 2013 - Mar 2018 (HHMI International Fellow) Research focus: 3D genome organization, enhancer-gene linking, regulatory . Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology . Computational Associate II, Stanley Center for Psychiatric Research Morgan Sheng | Broad Institute InBRAIN Collaboration Data Sharing Policy, Molecular and Cellular Neuroscience Program, Computationally-Enabled Integrative Neuroscience Program. Correlating atomic configurationsspecifically, degree of disorder (DOD)of an amorphous solid with properties is a long-standing riddle in materials science and condensed matter physics . 2018 Feb 5;217(2):459-472. doi: 10.1083/jcb.201709069. He joined NINDS as an investigator in 1997 and is now a tenured senior investigator . Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, 518052 P. R. China Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, 999077 . Our research is mainly focused on the RNA chemical modification and RNA structure biology. Professor of Biology; Core Member, Broad Institute; Investigator, Howard Hughes Medical Institute. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad's Stanley Center for Psychiatric Research. Get notified about new Research Scientist jobs in United States. A catalog of scientific papers published by our members and staff scientists. I am excited to return to academia and establish a research lab at the Broad, said Sheng. is located in Taipei. Many members of the faculty hold joint appointments with other departments at MIT and with outside institutions. A cleaning revolution: How JCS-Echigo partnered A*STAR to clean faster and smarter. See popular questions & answers about Broad Institute; Post-Doctoral Associate - Neuroscience Department. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. Sheng-Yong NIU | Cited by 405 | of Broad Institute of MIT and Harvard, MA | Read 19 publications | Contact Sheng-Yong NIU The role will often involve rapid prototyping in support of a dynamic, fast-moving experimental program; it is focused on molecular biology applications relevant to investigation of brain function and psychiatric illness. For a full list visit the lab website linked above. . People | Pan Group - Broad Institute 11:45 - 12:45 LUNCH & VIRTUAL SOCIALS Kate Mulherin. Faculty Assistant Mary Gidaro mgidaro@princeton.edu 105 Thomas Laboratory p 609-258-8956 f 609-258-1704. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. Fei Chen, Principal Investigator. Check out this video for a look into our community! Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology at Massachusetts General Hospital and Harvard Medical School (1994-2001) before joining MIT (2001-2008). yuansf@hku.hk. Dr. Sheng received his Ph.D. in Biochemistry from the University of Pennsylvania in 1993. TJ is an Instuctor in Dr. Ben Neale and Morgan Sheng's groups. Fusarium wilt of banana, especially Tropical Race 4 (TR4) is a major factor restricting banana production. This candidate will collaborate with biologists and geneticists to perform various . The labhas used a broad range of approaches to tackle these problems, notably the development of neuronal cultures from adult disease mouse models and live imaging of various organelle transport. There he built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. Research Areas . The research of her group focuses on translating emerging genetics into biology and to enable next-generation . Cardiac arrest and resuscitation activates the hypothalamic-pituitary Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations. in chemistry with honors from Caltech in 1999, and a . The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments. 2. Outstanding Achievement Award, Society of Chinese Bioscientists of American (SCBA) Neuroscience Division (2005). Researchers in the Sheng . 699 Bradley C. Paasch, Reza Sohrabi, Kinya Nomura & Sheng Yang He 700 701 . As the Director for Translational Neurobiology at Stanley Center, Dr. Pan aspires to translate the understanding of the genetics and biology of psychiatric and neurological illnesses to novel therapeutics for severe mental illnesses. Learn about Broad Institute's mentored research offerings for high school students, college students, and recent college graduates. sheng.ding@gladstone.ucsf.edu. From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. (1st class honors) from Oxford University and obtained his medical degree and training at London University. The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression. Broad Institute 4.0. Jin Sheng, Senior Technical Lead at Cisco Systems From 2008 to 2019, Sheng was Vice-President of Neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. Millions of years of co-evolution between plants and microbes have resulted in an intricate web of attack, counter-attack, decoy, and hijacking mechanisms in biology. Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Find us on Twitter. Registered Nurse. Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward. As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to shape the centers scientific vision and direction, and oversee the centers efforts to develop therapeutics for schizophrenia and other serious mental illnesses. Pursuing these investigations will advance our knowledge of fundamental processes that may affect human neurological disorders. EEO is The Law - click here for more information, Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled. Additionally, developing new . The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of theStanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. San Diego under the guidance of Professor Sheng Zhong. Abudayyeh-Gootenberg lab, McGovern Institute, and Zhang lab, McGovern Institute/Broad Institute Gloria Choi Image credit: Justin Knight/McGovern Institute. Neuron 29 (2), 353-366, 2001. Learn about breakthroughs from Broad scientists. Find out how to join the Broad as an employee or associate member. Laboratory Technician 1,190 job openings. Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue, From: https://picower.mit.edu/morgan-sheng, A physician and a scientist, Morgan Sheng. Morgan Sheng Broad Institute of MIT and Harvard Verified email at mit.edu. Shengs molecular studies of the structure and function of synapses (the communication junctions between brain cells) while at MGH and MIT have enhanced our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, neurodevelopmental disorders, and dementia. Dejanovic B, Huntley MA, De Mazire A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M. Neuron. In November 2022, Broads Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. and sequencing, takes ~3 d to process up to 192 samples manually. The scope will include integration with other internal and external genomics datasets. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the. From 2008 to 2019, Sheng was Vice-President of Neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. Queen's University. Ringel, Alison E. . Sheng started his academic career, centered on molecular and cellular neuroscience, in 1994 at Massachusetts General Hospital and Harvard Medical School, and later moved to MIT as the Menicon Professor of Neuroscience. He obtained his Ph.D. in biological engineering from the Massachusetts Institute of Technology in 2016. He completed his Ph.D. in 2016 at the Wellcome Trust Sanger Institute, where he studied the role of rare variation in the genetic architecture of psychiatric and neurodevelopmental disorders. sheng lab broad instituteaiken county sc register of deeds sheng lab broad institute sheng lab broad institute Broad brings people together to advance the understanding and treatment of disease. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). Steven E. Hyman, M.D., is a Harvard University Distinguished Service Professor of Stem Cell and Regenerative Biology and a Core Institute Member of the Broad Institute of Harvard and MIT, where he directs the Stanley Center for Psychiatric Research. Member of the Open Plastics consortium. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. Postdoctoral Associate - Xavier Lab: Broad Institute: Cambridge, MA: Post Doc Researcher - Social Media - Microsoft Research: Microsoft: Cambridge, MA: Postdoctoral fellow - Computational genetics and Genomics: Brigham & Women's Hospital(BWH) Boston, MA: Postdoctoral Associate - Sheng Lab: Broad Institute: Cambridge, MA Bio: Dr. Innis's laboratory uses novel positron emission tomography (PET) radioligands to measure neuroinflammation in volunteers with Alzheimer's disease and other dementias. As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to shape the centers scientific vision and direction, and oversee the centers efforts to develop therapeutics for schizophrenia and other serious mental illnesses. Massachusetts Institute of Technology M Sheng, S Smiga, A Bulfone, . By the end of 2022, Broads COVID-19 testing lab had processed more than 37 million tests. Postdoctoral Associate - Sheng Lab lab studies the neural mechanisms of attention, learning, and memory . This researcher will work in close collaboration with laboratory scientists on analysis of a range of projects with a strong emphasis on bulk RNA-seq and single cell approaches. Lab Administrator. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. Characterised the role of JNK signaling in posterior regeneration . AY Hung, M Sheng. Search job openings, see if they fit - company salaries, reviews, and more posted by The Broad Institute employees. Background and aimsAs a result of increasing numbers of studies most recently, mitophagy plays a vital function in the genesis of cancer. https://doi.org/10.1038/s41593-022-01251-x. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. Sheng returned to the department last fall as professor of neuroscience, a position he also held from 2001-08; the years in . Kingston, Ontario, Canada. Sheng J, Zhang W, Hassan A, Gan J, Soares A, Geng S, Ren Y, Huang Z. Hydrogen Bond Formation between the Naturally Modified Nucleobase and Phosphate Backbone. The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease. Agency for Science, Technology and Research (A*STAR) Her group has expertise in the physiology of ion channels, part of the large protein family critical to neurons firing and muscles moving. At Genentechhe built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. The Chen Lab. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. 46-1303 Yang uses biochemical and Lei is a postdoctoral researcher in the Pan Group at the Stanley Center for Psychiatric Research. JR Lee, AW Dunah, M Sheng, E Kim. PDF A critical role of a eubiotic microbiota in gating proper . Mailing address: California Institute of Technology. This study aimed to uncover and analyze the mitophagy-related diagnostic biomarkers in HCC using . The broad conservation of plant microbiota suggests that plants . Important new look into the Alzheimer's brain from a collaboration including Morgan Sheng, a Picower Institute affiliate professor based at . . NE30-6031. A past recipient of the Fondation Ipsen Prize in Neuronal Plasticity and the Young Investigator Award of the Society for Neuroscience, Sheng is author of more than 200 peer-reviewed publications focused on the molecular mechanisms underlying the structure and plasticity of synapses and the molecular-cell biology of neurodegeneration. Research Associate II - Stanley Center Therapeutics Virginia Tech Carilion Research Institute scientists have developed new imaging techniques to watch dangerous brain tumor cells respond to treatment in real time. The mechanisms of chemical reactions, including the transformation pathways of the electronic and geometric structures of molecules, are crucial for comprehending the essence and developing new chemistry. Nature neuroscience 12 (4), 428-437, 2009. . We seek to understand how lipid macromolecules are generated, stored, and metabolized, and how lipid processes function in membrane biology and cell physiology. 2012 - 2017 Ershela Durresi, Ph.D. Medical Student, Harvard Medical School . Email. Developing a resistant cultivar and inducing plant defenses by elicitor application are currently two of the best options to control this disease. The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric Research . Research Focus: 3D genome architecture. Sheng is a fellow of the Royal Society (UK), a fellow of the Academy of Medical Sciences (UK), a fellow of the American Association for the Advancement of Science, and honorary fellow of Corpus Christi College, Oxford. 30 The Broad Institute Postdoctoral Chemistry jobs in Us. US 5849868 A Bionet Corp. - New Taipei City 235 (Zhonghe District), 11, No.738, Jho 4 BCS News | Fall 2020 By Rachel Donahue Lab studies the genetics underlying neural development to identify new diagnostic and therapeutic approaches for a broad range of disorders that compromise brain and organ system development. Yun-Sheng Chen is an assistant professor at the University of Illinois, Urbana-Champaign. DOI: 10.1115/1.4054996 Corpus ID: 250577941; Design and Control of SLPM Based Extensible Continuum Arm @article{Zhuang2022DesignAC, title={Design and Control of SLPM Based Extensible Continuum Arm}, author={Zheming Zhuang and Ze-Sheng Zhang and Yuntao Guan and Wei Wei and Mi Li and Zhao Tang and Rongjie Kang and Zhibin Song and Jian Sheng Dai}, journal={Journal of Mechanisms and Robotics . The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region. Featuring speakers from the Wilson, Tonegawa, and Miller labs.. Moderated by BU Professor and Tonegawa lab alumnus Steve Ramirez. The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. Sheng completed his medical training and a residency in general medicine in London, UK. In the past few years, Pan has been working on genes whose dysfunction has been implicated for psychiatric illnesses using molecular, cellular, and electrophysiological approaches, both in vitro and in animals. Fralin Biomedical Research Institute faculty conduct research in wet and dry labs in our 280,000-square-foot facilities . The Chen Lab - People The P4 lab is located in a new developing zone about one hour car ride from the current institute location in central Wuhan city. Postdoctoral Fellowship Opening | NINDS Division of Intramural Research Dr. Sheng Ding is currently William K. Bowes, Jr. Geplaatst op 3 juli 2022 door Sheng and coworkers made important discoveries regarding the molecular mechanisms of synapse weakening and loss, the contributions of microglia and innate immunity in neurodegenerative diseases, and the roles of genetic risk factors in the pathogenesis of Alzheimers disease, Parkinsons disease, ALS, and frontotemporal dementia. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad's Stanley Center for Psychiatric Research. Morgan Sheng, Ph.D. Vice President of Neuroscience, Genentech, Inc., San Francisco, CA. I am currently an Associate Computational Biologist II in the Morgan Sheng lab at the Broad Institute of MIT and Harvard. Broad Institute of MIT and Harvard; Simons Center for the Social Brain; Massachusetts Institute of Technology