Grape seed extract may have heart-health benefits. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. (13). DOI: Luzzi R, et al. Whole Foods Organic Allergy Medicine-drug They were treated with 200 mg of Pycnogenol daily or with placebo. These benefits appeared to persist for some time even after stopping supplementation [72]. It also appeared to improve their attention span, visual motor skills, and concentration. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. 6 Amazing Benefits of Nattokinase | Organic Facts Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Pycnogenol treatment resulted in more normal-looking sperm. A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. The specific tree from which the bark is extracted is called a maritime pine. During week, five without, treatment, reduction of cramps was maintained in all three groups. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Your email address will not be published. For people who have symptoms that are more severe, traditional medicine is probably more effective. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. In one trial of 77 people with type 2 diabetes, pycnogenol (100 mg/day) for 12 weeks lowered both blood sugar levels and HbA1c, a marker of long-term blood glucose levels [31]. It seems to lower blood pressure and improve blood flow to the legs. It may cause side effects such as: Dizziness. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. The positive improvements in symptoms were greater among those taking Pycnogenol. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. Chemistry. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. Boost gastrointestinal health. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. 14 Health Benefits of Pine Bark Extract - Blog - iHerb.com It has many health benefits, and may help protect against several chronic conditions. As a skin powder, however, you can use it safely for up to six weeks. but is for informational and educational purposes alone. from the bark of the French maritime pine tree. New research shows . Lower Your Blood Pressure Naturally with Nattokinase SelfDecode does not treat, diagnose or cure any conditions, In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Quality and active ingredients in supplements may vary widely from maker to maker. Procyanidins are chain-like structures consisted of catechins similar to some found in green tea (the green tea catechins that do not have 'gallate' in their names). Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. Pycnogenol and Pine Bark Extract Supplements. While these results are promising, there isnt enough research to fully understand the effect of antioxidant levels on ADHD symptoms. Interactions. A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". whole-body health. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. Start with a low dose so you can be sure it doesnt cause any side effects. ( 4) Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. High levels of both of these are considered risk factors for heart disease. Pycnogenol significantly improved the heavy feeling as well as the swelling. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. This nerve affects our balance and hearing by sending signals to the brain. Side effects. It also reduced the size of scars. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . Ask your doctor for advice. Here are 12 benefits of ginkgo biloba. ( 1) 2. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. Pycnogenol has four main components that contribute to its benefits for men's health. Dr. Eric L. Zielinski is a sought-after natural . Pycnogenol: French maritime pine bark extract In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. nausea. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. Eliminate blood clots. Prunes and prune juice have many health benefits. (2004). Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. Top Anti-Aging Properties Of Pycnogenol - Life Extension New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. Andrographis is a medicinal herb used to treat many health conditions, such as the common cold, osteoarthritis, and ulcerative colitis. Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. She loves communicating science and empowering people to achieve their optimal health. Pycnogenol: Health Benefits, Side Effects, Uses, Dose - RxList According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Add to Cart. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Possible side effects . Any medication that you take, including herbal supplements, comes with certain risks. Joe Cohen flipped the script on conventional and alternative medicine and it worked. Lowers Blood Pressure. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. 2005 - 2023 WebMD LLC. The Benefits of DIM - Fort Wayne Physical Medicine Benefits Of Pycnogenol To Live Longer - Life Extension Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. Consequently, blood pressure is lowered. But the actual bioavailability of this complex mixture is still unknown. Taking pine bark extract also increases the blood . Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. Add to Cart. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Chanca Piedra: Benefits, Dosage, Side Effects, and More - Healthline The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. As a skin cream, its safe to use for about seven days. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. The standard dose appears to be 100-200 mg/day. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. Organika Pycnogenol 50mg 100 Tablets. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. But, as you know, going for the natural approach can make a huge difference in overall health. The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. Let us discuss them in detail below. Pycnogenol seems to help with asthma and allergies. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. What Are the Dangers of Pycnogenol? | Live Healthy - Chron The dosage in most clinical studies varied between 50-360 mg/day. It does this by improving the time it takes the body to reach a fatigued state through increased serum NAD+ levels. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. (7). (2015). Helps Treat Erectile Dysfunction. A study of 30 women found that Pycnogenol (75 mg/day) may reduce the skin area affected by melasma as well as lower symptoms of fatigue, constipation, body pain, and anxiety [62]. Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. According to the National Institutes of Health, its safe for adults to take 50 to 450 milligrams of pine bark extract daily for up to one year. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. 2005-2023 Healthline Media a Red Ventures Company. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. That way, your doctor can check on any potential side effects or interactions with medications. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Health Benefits of L-Arginine - WebMD A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. What Are These Tiny Red Spots on My Skin (Petechiae)? Natural Factors Pycnogenol 25mg 60 Veggie Caps. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. 1 Anti-Aging Beverage, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, What Is a Marionberry? In a good-quality study, 24 adults aged 24 to 53 years old with attention deficit hyperactivity disorder (ADHD) were given Pycnogenol, placebo, or the standard drug for three weeks. Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. The New Pycnogenol Benefits | Dr. Steven Lamm - YouTube 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. There's good evidence that pycnogenol helps with eye damage caused by diabetes. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. Pycnogenol health benefits. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. 12 Benefits of Pycnogenol (Pine Bark Extract) According to Studies Pycnogenol completely normalized function. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Benefits, Nutrition, Uses & How It Compares vs. Blackberries. chronic anal fissure may take more than 6 weeks to heal. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. DOI: Chowdhury WK, et al. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Pycnogenol may stimulate the immune system. It can also be used for local application on the skin without the risk of side effects. COPD. Research into Pycnogenol has revealed some promising results in over 30 health conditions. Some health benefits of Pycnogenol include:. This bark extract has been around for about 450 years. New Study: Daily Use of Pycnogenol Provides Benefits for Men Managing While OPCs found in this extract are mostly known for their antioxidant-producing benefits, these amazing compounds exude antibacterial, antiviral, anticarcinogenic, anti-aging, anti-inflammatory and anti-allergic properties. Pycnogenol is a compound of natural chemicals. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Possess Anti-Inflammatory Action. Erythritol: Is This Healthy Sweetener the Real Deal? This ensures that there is a healthy flow of blood to and from the heart. For mild high blood pressure: 200 milligrams daily. A trial of 86 people with eye damage from diabetes found that antioxidant therapy (including pycnogenol, vitamin E, and Coenzyme Q10) may improve eye health and reduce reactive oxygen species levels [35]. 6 Vinpocetine Benefits + How It Works & Side Effects She is a strong advocate of integrating scientific knowledge and holistic medicine. Studies have found that supplementing with pycnogenol effectively strengthens the blood vessels, stabilizing blood pressure. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. As I mentioned, pine bark extract is superior when it comes to antioxidants. This makes it very hard to set a standard dose. Studies have also safely used Pycnogenol in children and during pregnancy. 3. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. Cigarette smoking increases platelet aggregation. This article explains which supplements are believed to be safe during pregnancy and which ones you should avoid. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . Regardless of what youre using it for, its best to start with the lowest possible dose. Pycnogenol in metabolic syndrome and related disorders [Abstract]. 32 Pycnogenol & Pine Bark Extract Benefits + Dosage Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . No side effects were noted, unlike its synthetic counterpart. In this study, 155 peri-menopausal women were enrolled in a double-blind, placebo-controlled study. Another study found this supplement can even halt progression of vision . You can refer to the National Institutes of Healths dosage guidelines for specific conditions. Blazs G, et al. If youre native to Oregon, you likely know all about marionberries. Low-dose Pycnogenol (30 mg/day) may reduce pain in pregnant women, particularly hip, joint, lower back, groin, and calf cramps in the third trimester [71]. . 2005 - 2023 WebMD LLC. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Pycnogenol; Pycnogenol. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Purity and potency of Pycnogenolare continuously monitored . New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. Abdominal pain was by far the most . Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. It also may help those on blood pressure medications to reduce their dose [32]. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Its likely that muscle recovery time improved as well due to the high antioxidants pine bark extract contains. Pycnogenol helps erectile dysfunction and diabetes through circulatory link Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. This supplement possibly activates the immune system. Learn more about how to get even skin tone. There are several causes for erectile dysfunction, such as neurological and psychological issues. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Align your health hacks with your genes for optimal health & cognitive function. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. It may cause side effects such as: Risks. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. . However, its unclear how clinically effective Pycnogenol is for most of these conditions due to the low quality of evidence. Pycnogenol treatment reduced the need for painkillers by 58% versus one percent in the placebo-treated group. Sort By. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [15]. Pycnogenol: Health Benefits, Uses, Doses, Safety Information - WebMD PQQ Supplements: Overview, Benefits, and Side Effects - Healthline 10 Day Erection Delay Sex Pills. Prenatal nutrition can be confusing. DOI: Marini A, et al. Some small studies suggest it may also protect against coronary artery disease and blood clots. This study adds to a body of research showing the benefits of Pycnogenol . Rating: 100%. Grape Seed Extract: Benefits, Side Effects, Dosage, and Interactions A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. blood in the urine. Grapes: Health Benefits, Nutrition, Recipes and Risks - Dr. Axe While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available.